Sulfuric Acid → 2-(4-Carbamylphenyl)oxazolo[5,4-b]pyridine

반응식

[C:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[O:10][C:11]3[C:16]([N:17]=2)=[CH:15][CH:14]=[CH:13][N:12]=3)=[CH:5][CH:4]=1)#[N:2].S(=O)(=O)(O)[OH:19]>>[C:1]([C:3]1[CH:4]=[CH:5][C:6]([C:9]2[O:10][C:11]3[C:16]([N:17]=2)=[CH:15][CH:14]=[CH:13][N:12]=3)=[CH:7][CH:8]=1)(=[O:19])[NH2:2]

참가 물질

반응물 2

HCID 1118Sulfuric Acid

HCID 124614172-(4-Cyanophenyl)oxazolo[5,4-b]pyridine

생성물 1

HCID 227548262-(4-Carbamylphenyl)oxazolo[5,4-b]pyridine

실험 절차

A solution of 600 mg. of 2-(4-cyanophenyl)oxazolo[ 5,4-b]pyridine in 8 ml. of concentrated sulfuric acid was allowed to stand at room temperature for 16 hours. The solution was poured onto ice and the white precipitate was collected on a filter to give 2-(4-carbamylphenyl)oxazolo[ 5,4-b]pyridine, m.p. 315° C. (dec.).

후처리

additionThe solution was poured onto ice
customthe white precipitate was collected on
filtrationa filter

출처 및 근거

ORD 기록: ord-1345421afe24400491448826d60e1319
출처 데이터셋: uspto-grants-1977_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04038396

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