Phosphinic Acid → 1-Benzhydrylamino-2-methylpropanephosphonous acid

HRID 25973

반응식

HRID 25973 반응식
[PH2:1]([OH:3])=[O:2].[CH:4](=[N:8][CH:9]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[CH:5]([CH3:7])[CH3:6]>C(O)C>[CH:9]([NH:8][CH:4]([P:1]([OH:3])[OH:2])[CH:5]([CH3:7])[CH3:6])([C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

참가 물질

4

반응물 2

HCID 4124402Phosphinic AcidHCID 10657527Isobutylidenebenzhydrylamine

생성물 1

HCID 213258821-Benzhydrylamino-2-methylpropanephosphonous acid

시약·촉매·용매 1

HCID 702Ethanol용매2회

실험 절차

Hypophosphorous acid (100%, 15.8 parts) dissolved in absolute ethanol was added to a stirred solution of 41.3 parts isobutylidenebenzhydrylamine in absolute ethanol. An exothermic reaction occurred. After standing one hour the reaction was filtered and the white solid dried in vacuo. There was obtained DL-1-benzhydrylamino-2-methylpropanephosphonous acid, melting point 191° (dec.).

후처리

  1. customAn exothermic reaction
  2. filtrationthe reaction was filtered
  3. customthe white solid dried in vacuo

출처 및 근거

ORD 기록
ord-bee6e3df24624b6d98464e0a489e9362
출처 데이터셋
uspto-grants-1979_04
특허 번호
US04147780

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