Acetaldehyde → 1-Benzhydrylaminoethane phosphonous acid

HRID 25982노트

반응식

HRID 25982 반응식
[CH:1](=O)[CH3:2].[PH2:4]([O-:6])=[O:5].[CH:7]([NH3+:20])([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>O1CCOCC1>[CH:7]([NH:20][CH:1]([P:4]([OH:6])[OH:5])[CH3:2])([C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

참가 물질

4

반응물 2

HCID 177AcetaldehydeHCID 178527021HCID 178527021, 화합물

생성물 1

HCID 213258901-Benzhydrylaminoethane phosphonous acid

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

0.5 Parts of freshly distilled acetaldehyde was added to a suspension of 2.5 parts of benzhydrylammonium hypophosphite in 10 parts of dioxan at room temperature and the mixture stirred for 15 minutes. The mixture was then heated slowly to 50° when solution occurred and a flocculent precipitate immediately formed. The mixture was allowed to cool to room temperature with vigorous stirring and the orange yellow solid filtered off washed with dioxan and ether and finally with a little cold ethanol to give DL-1-benzhydrylaminoethane phosphonous acid, melting point 220°-221°.

후처리

  1. temperatureThe mixture was then heated slowly to 50° when solution
  2. customa flocculent precipitate immediately formed
  3. stirringwith vigorous stirring
  4. filtrationthe orange yellow solid filtered off
  5. washwashed with dioxan and ether and finally with a little cold ethanol

출처 및 근거

ORD 기록
ord-c36872adac9c4d889b5e07045c57da1c
출처 데이터셋
uspto-grants-1979_04
특허 번호
US04147780

반응 노트

불러오는 중…