Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl 4-oxobutyrate → 1-Benzhydrylamino-3-carbomethoxypropanephosphonous acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl 4-oxobutyrate | HCID 83779 | — |
| 반응물 | Sodium | HCID 5360545 | — |
| 반응물 | HCID 178527021 | HCID 178527021 | — |
| 생성물 | 1-Benzhydrylamino-3-carbomethoxypropanephosphonous acid | HCID 21325897 | — |
반응 단계
5.8 parts of freshly distilled 3-carbomethoxypropionaldehyde in 10 parts of sodium-dried dioxan was added to a suspension of 12.4 parts benzhydrylammonium hypophosphite in 60 parts of sodium-dried dioxan at 100° and under nitrogen over 15 minutes. 40 Parts water/dioxan was removed by distillation during the addition such that the temperature remained at 100° or above. The resulting clear solution was cooled and diluted with an equal volume of alcohol to give DL-1-benzhydrylamino-3-carbomethoxypropanephosphonous acid, melting point 162°-164°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04147780 |
| 출처 데이터셋 | uspto-grants-1979_04 |
| ORD ID | ord-f07ea71693684b45bf4ee60818f6711a |
| 출처 메모 | uspto-grants-1979_04 |