Tetra-n-butylammonium 1-(3-nitrophenyl)ethanesulphonate → Tetra-n-butylammonium 1-(3-aminophenyl)ethanesulphonate

HRID 259919

반응식

HRID 259919 반응식
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]([S:12]([O-:15])(=[O:14])=[O:13])[CH3:11])[CH:7]=[CH:8][CH:9]=1)([O-])=O.[CH2:16]([N+:20]([CH2:29][CH2:30][CH2:31][CH3:32])([CH2:25][CH2:26][CH2:27][CH3:28])[CH2:21][CH2:22][CH2:23][CH3:24])[CH2:17][CH2:18][CH3:19]>[Pd].C(O)C>[NH2:1][C:4]1[CH:5]=[C:6]([CH:10]([S:12]([O-:15])(=[O:13])=[O:14])[CH3:11])[CH:7]=[CH:8][CH:9]=1.[CH2:29]([N+:20]([CH2:16][CH2:17][CH2:18][CH3:19])([CH2:21][CH2:22][CH2:23][CH3:24])[CH2:25][CH2:26][CH2:27][CH3:28])[CH2:30][CH2:31][CH3:32]

참가 물질

4

반응물 1

HCID 22917835Tetra-n-butylammonium 1-(3-nitrophenyl)ethanesulphonate

생성물 1

HCID 9803422Tetra-n-butylammonium 1-(3-aminophenyl)ethanesulphonate

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

반응 조건

온도
25 °C

실험 절차

0.2 g of 5% strength palladium on charcoal is added to a solution of 2.8 g of the laevorotatory isomer of tetra-n-butylammonium 1-(3-nitrophenyl)ethanesulphonate in 50 cm3 of ethanol. The suspension is stirred for 2 hours at a temperature of about 25° C. under a hydrogen atmosphere (100 kPa). The catalyst is filtered off and the filtrate is concentrated to dryness under reduced pressure (2.7 kPa) at 40° C. 2.8 g of the laevorotatory isomer of tetra-n-butylammonium 1-(3-aminophenyl)ethanesulphonate are thus obtained in the form of an oil, used as such in the subsequent syntheses.

후처리

  1. filtrationThe catalyst is filtered off
  2. concentrationthe filtrate is concentrated to dryness under reduced pressure (2.7 kPa) at 40° C

출처 및 근거

ORD 기록
ord-e4772676ca694072bc9fb6329cecc7d7
출처 데이터셋
uspto-grants-1996_06
특허 번호
US05523469

연결된 노트

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