Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → 2-Amino-5-fluorobenzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | 2-Bromo-5-fluorobenzoic acid | HCID 2778181 | — |
| 반응물 | Sodium | HCID 5360545 | — |
| 반응물 | Potassium | HCID 5462222 | — |
| 용매 | Potassium Hydroxide | HCID 14797 | — |
| 생성물 | 2-Amino-5-fluorobenzoic acid | HCID 101412 | — |
반응 단계
If the sodium salt solution of 5-fluoro-2-bromobenzoic acid is replaced by aliquot parts of the potassium or ammonium salt solution, prepared by dissolving 219 parts of 5-fluoro-2-bromobenzoic acid in 256.1 parts of 21.9% strength aqueous potassium hydroxide or, respectively, 217 parts of 7.9% aqueous ammonia solution and used as the metering medium in a procedure otherwise identical to that indicated, then 5-fluoroanthranilic acid is obtained in identical yield and quality.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05523472 |
| 출처 데이터셋 | uspto-grants-1996_06 |
| ORD ID | ord-4f2f20decea5457bb0487fd375f40d1a |
| 출처 메모 | uspto-grants-1996_06 |