Toluene → HCID 11030613, 화합물

HRID 259985노트

반응식

HRID 259985 반응식
[Cl:1][C:2]([CH2:4]Cl)=[CH2:3].[CH2:6]([OH:13])[CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].C1(C)C=CC=CC=1>[Zn].O>[Cl:1][C:2](=[CH2:3])[CH2:4][CH:6]([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])[OH:13]

참가 물질

6

반응물 3

HCID 1140TolueneHCID 65652,3-DichloropropeneHCID 8129Heptanol

생성물 1

HCID 11030613HCID 11030613, 화합물수율 94.1%

시약·촉매·용매 2

HCID 23994Zinc촉매2회HCID 962Water용매

실험 절차

58.30 Grams of 2,3-dichloro-1-propene were added dropwise to a mixture of 30.00 g of heptanol, 90 g of toluene, 120 g of water and 34.35 g of zinc powder at 45° C., and then the resultant mixture was allowed to react at the same temperature for 10 hours. After the reaction finished, zinc-derived insolubles were filtered off, and the resultant filtrate was subjected to separation. The organic phase was washed with a 7% sodium carbonate aqueous solution and then dried over sodium sulfate. The desiccant was filtered off, and then the toluene was distilled off under reduced pressure to give 47.14 g of 2-chloroallyl-n-hexylcarbinol. The results were as follows.

후처리

  1. customto react at the same temperature for 10 hours
  2. filtrationwere filtered off
  3. customthe resultant filtrate was subjected to separation
  4. washThe organic phase was washed with a 7% sodium carbonate aqueous solution
  5. dry with materialdried over sodium sulfate
  6. filtrationThe desiccant was filtered off
  7. distillationthe toluene was distilled off under reduced pressure

출처 및 근거

ORD 기록
ord-061686e02a614a8e9eb59b3351843f22
출처 데이터셋
uspto-grants-1996_06
특허 번호
US05523495

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