홈MCP워크벤치Skills
홈워크벤치알림마이페이지
llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
  1. 홈
  2. /반응

Sodium Iodide → Tris-(2,2,6,6-tetramethylbenzo[1,2-d:5,4-d']-bis(1,3)oxathiol-4-yl) methanol

HRID 2602
노트
인쇄 미리보기

반응식

HRID 2602 반응식
C[Si](C)(C)[C:3]1[C:16]2[O:15][C:14]([CH3:18])([CH3:17])[S:13][C:12]=2[C:11]([C:19]([C:41]2[C:49]3[S:50][C:51]([CH3:54])([CH3:53])[O:52][C:48]=3[C:47]([Si](C)(C)C)=[C:46]3[C:42]=2[S:43][C:44]([CH3:60])([CH3:59])[O:45]3)([C:21]2[C:29]3[S:30][C:31]([CH3:34])([CH3:33])[O:32][C:28]=3[C:27]([Si](C)(C)C)=[C:26]3[C:22]=2[S:23][C:24]([CH3:40])([CH3:39])[O:25]3)[OH:20])=[C:5]2[S:6][C:7]([CH3:10])([CH3:9])[O:8][C:4]=12.[I-].[Na+].Cl[Si](C)(C)C.C([O-])(O)=O.[Na+]>C(#N)C>[CH3:39][C:24]1([CH3:40])[S:23][C:22]2=[C:21]([C:19]([C:11]3[C:12]4[S:13][C:14]([CH3:18])([CH3:17])[O:15][C:16]=4[CH:3]=[C:4]4[C:5]=3[S:6][C:7]([CH3:10])([CH3:9])[O:8]4)([C:41]3[C:42]4[S:43][C:44]([CH3:59])([CH3:60])[O:45][C:46]=4[CH:47]=[C:48]4[C:49]=3[S:50][C:51]([CH3:53])([CH3:54])[O:52]4)[OH:20])[C:29]3[S:30][C:31]([CH3:33])([CH3:34])[O:32][C:28]=3[CH:27]=[C:26]2[O:25]1
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

6

반응물 4

HCID 5238Sodium IodideHCID 6397ChlorotrimethylsilaneHCID 516892Sodium BicarbonateHCID 86752300Tris-(8-trimethylsilyl-2,2,6,6-tetramethylbenzo[1,2-d:5,4-d']-bis(1,3)oxathiol-4-yl)methanol

생성물 1

HCID 70260507Tris-(2,2,6,6-tetramethylbenzo[1,2-d:5,4-d']-bis(1,3)oxathiol-4-yl) methanol

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

Tris-(8-trimethylsilyl-2,2,6,6-tetramethylbenzo[1,2-d:5,4-d']-bis(1,3)oxathiol-4-yl)methanol (0.62 g, 0.62 mmol) was dissolved in acetonitrile (150 mL). Sodium iodide (0.75 g, 6.0 mmol) and chlorotrimethylsilane (0.65 g, 6.0 mmol) was added in one portion. The mixture was stirred for 20 min and then poured onto diethyl ether/aq. NaHCO3. The aqueous layer was extracted with ether and the combined organic layers were washed twice with water, dried (Na2SO4), evaporated, chromatographed (silica gel; dichloromethane) and finally triturated with ethyl acetate to yield the product as slightly brown crystals.

후처리

  1. additionpoured onto diethyl ether/aq
  2. extractionThe aqueous layer was extracted with ether
  3. washthe combined organic layers were washed twice with water
  4. dry with materialdried (Na2SO4)
  5. customevaporated
  6. customchromatographed (silica gel; dichloromethane)
  7. customfinally triturated with ethyl acetate
  8. customto yield the product as slightly brown crystals

출처 및 근거

ORD 기록
ord-3f677304111d45a7802ed37ac3c6141c
출처 데이터셋
uspto-grants-1998_03
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US05728370

반응 노트

불러오는 중…

이 페이지에서참가 물질실험 절차후처리출처 및 근거반응 노트