Phosgene → 2,6-Diethyl-4-nitrophenylisocyanate
반응식
[C:1](Cl)(Cl)=[O:2].[CH2:5]([C:7]1[CH:13]=[C:12]([N+:14]([O-:16])=[O:15])[CH:11]=[C:10]([CH2:17][CH3:18])[C:8]=1[NH2:9])[CH3:6]>C1(C)C=CC=CC=1>[CH2:17]([C:10]1[CH:11]=[C:12]([N+:14]([O-:16])=[O:15])[CH:13]=[C:7]([CH2:5][CH3:6])[C:8]=1[N:9]=[C:1]=[O:2])[CH3:18]참가 물질
4
실험 절차
Excess phosgene is bubbled into a warm solution of 21.5 g (0.11 moles) of 2,6-diethyl-4-nitroaniline in toluene (250 ml). After the addition, the mixture is heated to reflux and approximately 200 ml of toluene are distilled. The remainder of the toluene is removed under vacuum and the remaining brown semi-solid is distilled under vacuum to give 2,6-diethyl-4-nitrophenylisocyanate, b.p. 135°-144° C./1 mm, as a yellow liquid which crystallized on standing.
후처리
- additionAfter the addition
- temperaturethe mixture is heated
- temperatureto reflux
- distillationapproximately 200 ml of toluene are distilled
- customThe remainder of the toluene is removed under vacuum
- distillationthe remaining brown semi-solid is distilled under vacuum
출처 및 근거
- ORD 기록
- ord-f7fe7bcfb4234004b8032086d9231bf4
- 출처 데이터셋
- uspto-grants-1979_04
- 특허 번호
- US04147804
반응 노트
불러오는 중…