Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl Bromide → Diethyl 2-hydroxybenzene-1,4-dicarboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl Bromide | HCID 6332 | — |
| 반응물 | Bromoterephthalic acid | HCID 68513 | — |
| 반응물 | 2-Hydroxyterephthalic acid | HCID 97257 | — |
| 반응물 | 1,8-Diazabicyclo[5.4.0]undec-2-ene | HCID 9812821 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | Diethyl 2-hydroxybenzene-1,4-dicarboxylate | HCID 22401614 | — |
반응 단계
6.62 g of 1,8-diazabicyclo[5.4.0]undecene and 100 mL benzene were added to 3.76 g hydroxyterephthalic acid (synthesized from bromoterephthalic acid by a known method) and the mixture was heated. 6.76 g of bromoethane dissolved in 38 mL benzene was added dropwise in and the reaction mixture was heated under reflux for 19 hours. The salt product was filtered off, and purification by column chromatography then yielded 4.66 g diethyl hydroxyterephthalate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05527862 |
| 출처 데이터셋 | uspto-grants-1996_06 |
| ORD ID | ord-b3305a26870c4436b3ea5f4482976b00 |
| 출처 메모 | uspto-grants-1996_06 |