Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
M-Cresol → Cresatin
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | M-Cresol | HCID 342 | — |
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | Acetyl chloride | HCID 6367 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Cresatin | HCID 67406 | 97.2% |
반응 단계
To a solution of m-cresol (Aldrich) (80 g, 0.74 mol) in dry CH2Cl2 (300 mL) was added pyridine (71 mL, 0.89 mol) and at 0° C. was added dropwise acetyl chloride (58 mL, 0.81 mol). The reaction mixture was stirred for 1 h and then diluted with more CH2Cl2. The organic phase was washed successively with HCl 1N (3×), brine, dried over MgSO4 and evaporated. The residue was distilled under vacuum to give 108 g (97%) of the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05527827 |
| 출처 데이터셋 | uspto-grants-1996_06 |
| ORD ID | ord-b86af76b6d02406091ceb8a37c468bc4 |
| 출처 메모 | uspto-grants-1996_06 |