Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 4-Carbethoxyphenyl 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylmethyl ether
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Ethylparaben | HCID 8434 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 6-(Bromomethyl)-1,1,4,4-Tetramethyl-1,2,3,4-Tetrahydronaphthalene | HCID 2735597 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 4-Carbethoxyphenyl 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylmethyl ether | HCID 14850591 | 50.8% |
반응 단계
10 g (36 mmol) of 2-bromomethyl-5,6,7,8-tetrahydro-5,5,8,8-tetramethylnaphthalene, 6 g (36 mmol) of ethyl 4-hydroxybenzoate and 7.2 g (52 mmol) of anhydrous potassium carbonate in 60 ml of dimethylformamide were refluxed for 5.25 h. The mixture was then poured into water and extracted several times with ether, and the organic phase was washed with water, dried over Na2SO4 and concentrated. Recrystallization from methanol resulted in 6.7 g of the title compound of melting point 109°-11° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05527945 |
| 출처 데이터셋 | uspto-grants-1996_06 |
| ORD ID | ord-f75bbc7f4d8a4c7187ebdf2b499a8401 |
| 출처 메모 | uspto-grants-1996_06 |