Ethyl 4-(3-benzyloxycarbonyl-1-indolyl)-butyrate → 1-(3-Ethoxycarbonylpropyl)indole-3-carboxylic acid

HRID 260834노트

반응식

HRID 260834 반응식
C([O:8][C:9]([C:11]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[N:13]([CH2:20][CH2:21][CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])[CH:12]=1)=[O:10])C1C=CC=CC=1>C(O)C.[C].[Pd]>[CH2:26]([O:25][C:23]([CH2:22][CH2:21][CH2:20][N:13]1[C:14]2[C:19](=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:11]([C:9]([OH:10])=[O:8])=[CH:12]1)=[O:24])[CH3:27]

참가 물질

4

반응물 1

HCID 22400494Ethyl 4-(3-benzyloxycarbonyl-1-indolyl)-butyrate

생성물 1

HCID 224004721-(3-Ethoxycarbonylpropyl)indole-3-carboxylic acid

시약·촉매·용매 2

HCID 178418390HCID 178418390, 화합물촉매HCID 702Ethanol용매

실험 절차

A mixture of ethyl 4-(3-benzyloxycarbonyl-1-indolyl)-butyrate and 10% palladium carbon in ethanol was stirred at room temperature for 1.5 hours under a hydrogen atmosphere. Removal of the catalyst and evaporation of the solvent afforded the object product.

후처리

  1. customRemoval of the catalyst and evaporation of the solvent
  2. customafforded the object product

출처 및 근거

ORD 기록
ord-986e4b6206814c219fb52f8130a34804
출처 데이터셋
uspto-grants-1996_06
특허 번호
US05530019

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