3-Methoxybenzaldehyde → 3-methoxy-beta-methylstyrene Oxide
반응식
[C:1]1([SH+]C2C=CC=CC=2)C=CC=C[CH:2]=1.[CH3:14][O:15][C:16]1[CH:17]=[C:18]([CH:21]=[CH:22][CH:23]=1)[CH:19]=[O:20]>O1CCCC1>[CH3:14][O:15][C:16]1[CH:17]=[C:18]([CH:21]=[CH:22][CH:23]=1)[CH:19]1[O:20][CH:1]1[CH3:2]참가 물질
4
반응 조건
- 온도
- -78 °C
실험 절차
To a -78° C. solution of diphenylsulfonium ethylide (1.0 mole) in tetrahydrofuran (one liter) is slowly added 3-methoxybenzaldehyde (1.0 mole). The reaction mixture is stirred at -78° C. for 3 hours and then allowed to warm to room temperature. It is then added to ether-water and the ether phase separated. The ether phase is washed with water, dried (MgSO4) and evaporated. Fractional distillation of the residue gives the title product.
후처리
- customTo a -78° C.
- temperatureto warm to room temperature
- customthe ether phase separated
- washThe ether phase is washed with water
- dry with materialdried (MgSO4)
- customevaporated
- distillationFractional distillation of the residue
출처 및 근거
- ORD 기록
- ord-0870f23e94594ab8af2b681cf027407d
- 출처 데이터셋
- uspto-grants-1979_04
- 특허 번호
- US04147872
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