Allyl bromide → N-[4-(Allylsulfonyl)phenyl]acetamide

HRID 261156

반응식

HRID 261156 반응식
[C:1]([NH:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([OH:13])=[O:12])=[CH:7][CH:6]=1)(=[O:3])[CH3:2].C(=O)([O-])O.[Na+].[CH2:19](Br)[CH:20]=[CH2:21]>O>[CH2:21]([S:11]([C:8]1[CH:7]=[CH:6][C:5]([NH:4][C:1](=[O:3])[CH3:2])=[CH:10][CH:9]=1)(=[O:13])=[O:12])[CH:20]=[CH2:19]

참가 물질

5

반응물 3

HCID 7841Allyl bromideHCID 4121504-(Acetylamino)benzenesulfinic acidHCID 516892Sodium Bicarbonate

생성물 1

HCID 20375362N-[4-(Allylsulfonyl)phenyl]acetamide

시약·촉매·용매 1

HCID 962Water용매

실험 절차

50 parts of p-acetylaminophenylsulfinic acid and 25 parts of sodium hydrogen carbonate are suspended in 300 parts of water. While stirring intensely 36 parts of allyl bromide is dripped in within three hours at 50° to 60° C. Stirring is continued for another four hours at 60° C. 45 parts of p-allylsulfonylacetanilide is obtained with a melting point of 116° to 118° C.

후처리

  1. customis dripped in within three hours at 50° to 60° C

출처 및 근거

ORD 기록
ord-3665d53065634e9283f0125b5181815f
출처 데이터셋
uspto-grants-1979_08
특허 번호
US04164500

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