3-Methoxyacetophenone → Ethyl 3-(3-Benzyloxyphenyl)crotonate

반응식

[CH3:1][O:2][C:3]1[CH:4]=[C:5](/[C:9](/[CH3:16])=[CH:10]\[C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH:6]=[CH:7][CH:8]=1.CC([C:20]1[CH:25]=[CH:24][CH:23]=[C:22](OC)[CH:21]=1)=O.C(C=P(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)(OCC)=O>>[CH2:1]([O:2][C:3]1[CH:4]=[C:5](/[C:9](/[CH3:16])=[CH:10]\[C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH:6]=[CH:7][CH:8]=1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

참가 물질

반응물 3

HCID 114603-Methoxyacetophenone

HCID 70670Acetic acid, 2-(triphenylphosphoranylidene)-, ethyl ester

HCID 70595204(Z)-ethyl 3-(3-methoxyphenyl)but-2-enoate

생성물 1

HCID 70527588Ethyl 3-(3-Benzyloxyphenyl)crotonate

실험 절차

In like manner, ethyl 3-(3-methoxyphenyl)crotonate is prepared from 3-methoxyacetophenone (43.1 g.) and carbethoxymethylene triphenylphosphorane (200 g.).

출처 및 근거

ORD 기록: ord-8b9e6c5aa7f44d1085c999ff5d3ba9b4
출처 데이터셋: uspto-grants-1979_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04165323

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