Selenium Dioxide → 2-(3-(Benzyloxy)phenyl)-2-oxoacetaldehyde

HRID 261603

반응식

HRID 261603 반응식
[Se](=O)=O.[O:4]1CCOCC1.[CH3:10][C:11]([C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH2:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH:14]=1)=[O:12]>O>[CH2:20]([O:19][C:15]1[CH:14]=[C:13]([C:11]([CH:10]=[O:4])=[O:12])[CH:18]=[CH:17][CH:16]=1)[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

참가 물질

5

반응물 3

HCID 24007Selenium DioxideHCID 312751,4-DioxaneHCID 986891-(3-(Phenylmethoxy)phenyl)ethan-1-one

생성물 1

HCID 134580312-(3-(Benzyloxy)phenyl)-2-oxoacetaldehyde

시약·촉매·용매 1

HCID 962Water용매

실험 절차

To a solution of 9.4 g. of selenium dioxide in a solvent mixture of 50 ml. of dioxane and 1.7 ml. of water, was added 16.5 g. of 3-benzyloxyacetophenone. The mixture was refluxed for 4 hrs. with stirring. The resulting precipitates were removed by filtration and the solvents were distilled off from the filtrate under reduced pressure. The residue was dissolved in benzene and washed with water several times. After drying the benzene layer, benzene was removed by distillation to obtain the glyoxal as yellow liquid in a quantitative yield.

후처리

  1. temperatureThe mixture was refluxed for 4 hrs
  2. customThe resulting precipitates
  3. customwere removed by filtration
  4. distillationthe solvents were distilled off from the filtrate under reduced pressure
  5. dissolutionThe residue was dissolved in benzene
  6. washwashed with water several times
  7. dry with materialAfter drying the benzene layer, benzene
  8. customwas removed by distillation

출처 및 근거

ORD 기록
ord-5c05fd5f8379424e8e6798a5a0ae7acd
출처 데이터셋
uspto-grants-1979_08
특허 번호
US04166180

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