Benzyl formate → Phenylacetic Acid

HRID 261721

반응식

HRID 261721 반응식
C(O[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=O.[C]=[O:12].CN1CCC[C:15]1=[O:19]>>[C:5]1([CH2:4][C:15]([OH:19])=[O:12])[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=1

참가 물질

4

반응물 3

HCID 7708Benzyl formateHCID 13387N-methyl-2-pyrrolidoneHCID 178418416HCID 178418416, 화합물

생성물 1

HCID 999Phenylacetic Acid

실험 절차

The same autoclave as used in Example 17 is charged with 20 grams of benzyl formate, and 20 grams of N-methyl-2-pyrrolidone and 1.4 grams of mercurous iodide are added thereto. Carbon monoxide is introduced into the autoclave under pressure and the reaction is conducted at a pressure of 300 kg./cm.2 gauge and a temperature of 210° C. for 2 hours. As a result there is obtained phenyl acetic acid in a yield of 12.6 grams, which corresponds to a conversion of 63% based on the starting benzyl formate.

후처리

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출처 및 근거

ORD 기록
ord-bf7e23b2d70b452ca0f480b836e3a8ec
출처 데이터셋
uspto-grants-1979_05
특허 번호
USRE029981

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