2H-Benzimidazol-2-one, 1,3-dihydro-1-phenyl- → 4-Benzyl-2-(1-phenyl-2,3-dihydro-benzimidazol-2-on-3-yl-methyl)-morpholine

HRID 261785

반응식

HRID 261785 반응식
[C:1]1([N:7]2[C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=3[NH:9][C:8]2=[O:16])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl[CH2:18][CH:19]1[O:24][CH2:23][CH2:22][N:21]([CH2:25][C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH2:20]1>>[CH2:25]([N:21]1[CH2:22][CH2:23][O:24][CH:19]([CH2:18][N:9]2[C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=3[N:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)[C:8]2=[O:16])[CH2:20]1)[C:26]1[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=1

참가 물질

3

반응물 2

HCID 846572H-Benzimidazol-2-one, 1,3-dihydro-1-phenyl-HCID 28015624-Benzyl-2-(chloromethyl)morpholine

생성물 1

HCID 706018204-Benzyl-2-(1-phenyl-2,3-dihydro-benzimidazol-2-on-3-yl-methyl)-morpholine

실험 절차

The condensation of 0.1 mol of 1-phenyl-2,3-dihydro-benzimidazol-2-one and 0.1 mol of 2-chloromethyl-4-benzyl-morpholine in accordance with the procedure (a) of Example 1 gives, after evaporation of the solvent under reduced pressure, a pale pink solid which melts at about 90° C. and which is used as such for the subsequent operations.

후처리

  1. customgives
  2. customafter evaporation of the solvent under reduced pressure

출처 및 근거

ORD 기록
ord-25b17f710bfa40f6b3f9d4a5c591d0cc
출처 데이터셋
uspto-grants-1979_05
특허 번호
US04152434

연결된 노트

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