Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrazoic acid → HCID 178420316, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrazoic acid | HCID 24530 | — |
| 반응물 | Ammonium Chloride | HCID 25517 | — |
| 반응물 | Sodium Azide | HCID 33557 | — |
| 반응물 | 1-benzyl-1H-imidazole-2-carbaldehyde | HCID 139082 | — |
| 반응물 | 1H-Imidazole-2-carbonitrile, 1-(phenylmethyl)- | HCID 11030475 | — |
| 반응물 | HCID 178418441 | HCID 178418441 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | HCID 178420316 | HCID 178420316 | — |
반응 단계
Obtained by reacting 9.3 g (0.05 mol) of 1-benzyl-2-formylimidazole (see Liebigs Ann. Chem. 718 (1968) pp. 249-259) with 8.0 g (0.15 mol) of ammonium chloride and 9.8 g (0.15 mol) of sodium azide in 50 ml of dimethylformamide at 120°-130° C. The isolation of the 1-benzyl-2-cyanoimidazole intermediate (obtained by Schmidt-rearrangement) may be omitted, since this compound adds excess hydrazoic acid to the tetrazole in situ. After 20 hours, it is cooled, and 500 ml of water are added, the precipitate formed filtered off and recrystallised several times from dimethylformamide. M.p. 274°-275° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04152440 |
| 출처 데이터셋 | uspto-grants-1979_05 |
| ORD ID | ord-faced8bfa88b4593be37b6ecae11b106 |
| 출처 메모 | uspto-grants-1979_05 |