Hydrogen Peroxide → 3-Amino-5-phenyl-thiazolo-(4,5-c)-isothiazole
반응식
OO.[C:3]1([C:9]2[S:10][C:11]([C:15](=[S:17])[NH2:16])=[C:12]([NH2:14])[N:13]=2)[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1>CO>[NH2:16][C:15]1[S:17][N:14]=[C:12]2[N:13]=[C:9]([C:3]3[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=3)[S:10][C:11]=12참가 물질
4
반응 조건
- 온도
- 22 °C
실험 절차
7 parts of 30 percent strength by weight hydrogen peroxide are added to 12.8 parts of 2-phenyl-4-amino-5-thiocarbamoylthiazole in 150 parts of methanol. The mixture is stirred for 12 hours at 22° C. and the product is then filtered off. 7.9 parts of 3-amino-5-phenyl-thiazolo-(4,5-c)-isothiazole (62% of theory) of melting point 176°-179° C. are obtained.
후처리
- filtrationthe product is then filtered off
출처 및 근거
- ORD 기록
- ord-051bc14fa00b4a1c9af80e707cbbdeb9
- 출처 데이터셋
- uspto-grants-1979_05
- 특허 번호
- US04153607
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