Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 4-Chlorophenyl Isocyanate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Chloroform | HCID 6212 | — |
| 반응물 | 4-Chlorophenylurea | HCID 8796 | — |
| 반응물 | Sodium Nitrite | HCID 23668193 | — |
| 촉매 | Tetrabutylammonium Tetrafluoroborate | HCID 67932 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4-Chlorophenyl Isocyanate | HCID 7693 | — |
반응 단계
4-Chlorophenyl urea (8.5 parts) and a solution of sodium nitrite (6.9 parts) in water (10 parts) were added over 6 hours to a mixture of conc. hydrochloric acid (10.3 parts) chloroform (130 parts) and tetra-n-butyl ammonium fluoroborate (10% by weight based on 4-chlorophenyl urea) at -10° to -5° C. The mixture was stirred for a further 15 minutes then the stirrer stopped and layers allowed to separate. No solid was present at this stage. 5 mls of the organic layer was taken for analysis and the remainder kept cold until required.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04153624 |
| 출처 데이터셋 | uspto-grants-1979_05 |
| ORD ID | ord-b62cc6b7e3f94970b45c84cfc794cd41 |
| 출처 메모 | uspto-grants-1979_05 |