Boron trifluoride etherate → 3-(4-Chlorophenyl)-2,3-dihydro-1H-indole

HRID 262290노트

반응식

HRID 262290 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[NH:10][CH:9]=2)=[CH:4][CH:3]=1.B(F)(F)F.CCOCC>[Zn].C(O)(=O)C>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]2[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[NH:10][CH2:9]2)=[CH:6][CH:7]=1

참가 물질

5

반응물 2

HCID 8000Boron trifluoride etherateHCID 153224793-(4-Chlorophenyl)-1H-indole

생성물 1

HCID 537323163-(4-Chlorophenyl)-2,3-dihydro-1H-indole

시약·촉매·용매 2

HCID 23994Zinc촉매HCID 176Acetic Acid용매

실험 절차

Using the same procedure as detailed in Example 1 3.5 g of 3-p-chlorophenylindole, 35 ml of glacial acetic acid, 7 ml of boron trifluoride etherate and 7 g of zinc dust were reacted together and the product worked up as in Example 1. In this way 1.5 g of the desired 3-p-chlorophenylindoline was obtained as a yellow oil.

후처리

  1. customwere reacted together

출처 및 근거

ORD 기록
ord-463c4a091e8d4946bd3905f90794be79
출처 데이터셋
uspto-grants-1979_05
특허 번호
US04153789

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