Isopropylamine → HCID 21319067, 화합물

반응식

[CH3:1][N:2]1[C:11]([CH2:12][CH2:13][C:14]2[CH:19]=[CH:18][C:17]([O:20][CH2:21][CH:22]3[O:24][CH2:23]3)=[C:16]([O:25][CH3:26])[CH:15]=2)=[CH:10][C:9]2[C:4](=[CH:5][C:6]([O:27][CH3:28])=[CH:7][CH:8]=2)[C:3]1=[O:29].[CH:30]([NH2:33])([CH3:32])[CH3:31]>>[CH3:1][N:2]1[C:11]([CH2:12][CH2:13][C:14]2[CH:19]=[CH:18][C:17]([O:20][CH2:21][CH:22]([OH:24])[CH2:23][NH:33][CH:30]([CH3:32])[CH3:31])=[C:16]([O:25][CH3:26])[CH:15]=2)=[CH:10][C:9]2[C:4](=[CH:5][C:6]([O:27][CH3:28])=[CH:7][CH:8]=2)[C:3]1=[O:29]

참가 물질

반응물 2

HCID 6363Isopropylamine

HCID 21319052HCID 21319052, 화합물

생성물 1

HCID 21319067HCID 21319067, 화합물수율 80%

실험 절차

2-Methyl-3-[3-methoxy-4-(2-hydroxy-3-isopropylamino-propoxy)-phenethyl]-7-methoxy-isoquinolin-1(2H)-one was prepared analogous to Example 1b from 2-methyl-3-[3-methoxy-4-(2,3-epoxypropoxy)-phenethyl]-7-methoxy-isoquinolin-1(2H)-one and isopropylamine.

출처 및 근거

ORD 기록: ord-9ee5dee58fb24bad933aacd6d9b72fe9
출처 데이터셋: uspto-grants-1979_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04154837

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