Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 2-nitro-7-dimethylamino-6,7-dihydro [5H] benzocycloheptene hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Dimethylamine | HCID 674 | — |
| 반응물 | 8,9-dihydro-3-nitro-5H-benzocyclohepten-5-one | HCID 20094732 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 2-nitro-7-dimethylamino-6,7-dihydro [5H] benzocycloheptene hydrochloride | HCID 86736536 | — |
반응 단계
Using the procedure of Example 1, 3-nitro-8,9-dihydro [5H] benzocycloheptene-5-one and dimethylamine were reacted to obtain a non-salified product which was treated in ethyl acetate with a solution of ethyl acetate saturated with gaseous hydrogen chloride to obtain a product which was crystallized from isopropanol to obtain 2-nitro-7-dimethylamino-6,7-dihydro [5H] benzocycloheptene hydrochloride melting at 202° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04154852 |
| 출처 데이터셋 | uspto-grants-1979_05 |
| ORD ID | ord-90242655c5d1464691f6d4744eae6f66 |
| 출처 메모 | uspto-grants-1979_05 |