Formicin → 3-Acetamidomethylthio-2-methylpropanoic acid

HRID 262582노트

반응식

HRID 262582 반응식
[SH:1][CH2:2][CH:3]([CH3:7])[C:4]([OH:6])=[O:5].O[CH2:9][NH:10][C:11](=[O:13])[CH3:12]>FC(F)(F)C(O)=O>[C:11]([NH:10][CH2:9][S:1][CH2:2][CH:3]([CH3:7])[C:4]([OH:6])=[O:5])(=[O:13])[CH3:12]

참가 물질

4

반응물 2

HCID 69365FormicinHCID 1529103-Mercaptoisobutyric acid

생성물 1

HCID 213191453-Acetamidomethylthio-2-methylpropanoic acid

시약·촉매·용매 1

HCID 6422Trifluoroacetic acid용매

실험 절차

3-Mercapto-2-methylpropanoic acid (2.4 g.) and N-hydroxymethylacetamide (1.8 g.) are dissolved in trifluoroacetic acid and the solution is stored at room temperature for one hour. The trifluoroacetic acid is removed in vacuo and the residue is dried in vacuo over potassium hydroxide to yield 3-acetamidomethylthio-2-methylpropanoic acid.

후처리

  1. customThe trifluoroacetic acid is removed in vacuo
  2. dry with materialthe residue is dried in vacuo over potassium hydroxide

출처 및 근거

ORD 기록
ord-0608b8bc62914d75bd49bba4023019fe
출처 데이터셋
uspto-grants-1979_05
특허 번호
US04154840

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