Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Formaldehyde → (1,4-dimethyl-1H-imidazol-2-yl)methanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Formaldehyde | HCID 712 | — |
| 반응물 | (5,6,7,8-Tetrahydroimidazo[1,5-a]pyridin-3-yl)methanol | HCID 12923422 | — |
| 반응물 | Butyllithium | HCID 178418339 | — |
| 생성물 | (1,4-dimethyl-1H-imidazol-2-yl)methanol | HCID 12923402 | — |
반응 단계
The reaction of 1,4-dimethylamidazole (5.65 g.) with n-butyl lithium followed by treatment with formaldehyde (according to the method described for the preparation of 3-hydroxymethyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine in Example 243) gave 1,4-dimethyl-2-hydroxymethylimidazole (2.71 g.), m.p. 125°-126° (ethyl acetate-petroleum ether).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04154844 |
| 출처 데이터셋 | uspto-grants-1979_05 |
| ORD ID | ord-600d33573d3948dab7ef1f782a87ba80 |
| 출처 메모 | uspto-grants-1979_05 |