참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | O,O-diethyl phosphorochloridothioate | HCID 17305 | — |
| 반응물 | 2-Cyano-3-hydroxy-5-methyl-thiophene | HCID 21317929 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 2-Cyano-3-(diethoxythiophosphoryloxy)-5-methyl-thiophene | HCID 54246050 | 76.4% |
반응 단계
7 g of potassium carbonate and 9.5 g of O,O-diethyl chlorothiophosphate were added to a solution of 7 g of 2-cyano-3-hydroxy-5-methyl-thiophene in 100 ml of acetone and the mixture was stirred for 15 hours at 20° C. and was then filtered. The filtrate was evaporated to dryness and the residue was chromatographed over silica gel. Elution with an 8-2 cyclohexane-ethyl acetate mixture yielded 11.2 g of 2-cyano-3-(diethoxythiophosphoryloxy)-5-methyl-thiophene with a refractive index of nD20 =1.534.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04155996 |
|---|
| 출처 데이터셋 | uspto-grants-1979_05 |
|---|
| ORD ID | ord-01b6035c65ea4f1a9e8bb1f6daf14852 |
|---|
| 출처 메모 | uspto-grants-1979_05 |
|---|
