참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | O,O-diethyl phosphorochloridothioate | HCID 17305 | — |
| 반응물 | 5-Butoxy-3-hydroxythiophene-2-carbonitrile | HCID 21317900 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 2-Cyano-3-(diethoxythiophosphoryloxy)-5-n-butoxy-thiophene | HCID 54416426 | 80.6% |
반응 단계
7 g of potassium carbonate and 9.4 g of O,O-diethyl chlorothiophosphate were added to a solution of 9.8 g of 2-cyano-3-hydroxy-5-n-butoxy-thiophene in 150 ml of acetonitrile and the mixture was stirred for 24 hours at 20° C. and was filtered. The filtrate was evaporated to dryness under reduced pressure and the residue was chromatographed over silica gel. Elution with benzene yielded 14 g of 2-cyano-3-(diethoxythiophosphoryloxy)-5-n-butoxy-thiophene with a refractive index of nD20 =1.525.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04155996 |
|---|
| 출처 데이터셋 | uspto-grants-1979_05 |
|---|
| ORD ID | ord-50c477b0f52c4dcbb3707af80acb45b0 |
|---|
| 출처 메모 | uspto-grants-1979_05 |
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