Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Oxetane → 3-[N'-(3-Hydroxypropyl)-N'-methylamino]-N,N,N-trimethyl-1-propanaminium Bromide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Oxetane | HCID 10423 | — |
| 반응물 | N,N,N-Trimethyl-3-(methylamino)propan-1-aminium bromide | HCID 21444211 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-[N'-(3-Hydroxypropyl)-N'-methylamino]-N,N,N-trimethyl-1-propanaminium Bromide | HCID 23347568 | — |
반응 단계
A mixture of 20 g. of oxetane (0.34 mole), 32.8 g. of N,N,N-trimethyl-[3-(methylamino)]-1-propanaminium bromide (0.156 mole) and 22 ml. water is heated in a sealed tube at 100° for 15 hours. The solution is evaporated in vacuo and the residue is dissolved in 50 ml. of acetonitrile and filtered. Upon evaporation the desired product crystallizes. The product may be recrystallized from acetonitrile.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04156693 |
| 출처 데이터셋 | uspto-grants-1979_05 |
| ORD ID | ord-f2c120316ee347cb8ea232a7c1248f59 |
| 출처 메모 | uspto-grants-1979_05 |