Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(1-Isopropylpiperidin-4-yl)methanamine → 2-Chloropropane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (1-Isopropylpiperidin-4-yl)methanamine | HCID 7258859 | — |
| 반응물 | 3-Chloro-6-chlorocarbonylphenylsulfenyl chloride | HCID 10728826 | — |
| 생성물 | 2-Chloropropane | HCID 6361 | — |
| 생성물 | N-(piperidin-4-ylmethyl)acetamide | HCID 4341747 | — |
반응 단계
2-(1-sopropylpiperid-4-ylmethyl)-6-chloro-1,2-benzisothiazolin-3-one is obtained analogously to Example 33 by reacting 3-chloro-6-chlorocarbonylphenylsulfenyl chloride and 1-isopropyl-4-aminomethylpiperidine [boiling point 15 :95°-97° C.; obtained from 4-acetylaminomethylpiperidine and isopropyl chloride analogously to Singh et al., J. Med. Chem. 12, 949 (1969) and Werbel et al., supra]. After recrystallization in acetone, yellow crystals of melting point 134°-135° C. are obtained; yield: 37% of theory.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04156729 |
| 출처 데이터셋 | uspto-grants-1979_05 |
| ORD ID | ord-96feb2b4c82e4f69ac86803b109e0cef |
| 출처 메모 | uspto-grants-1979_05 |