Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
tert-Butyl isocyanate → N-(1-cyanoethyl)-N'-(1,1-dimethylethyl)urea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | tert-Butyl isocyanate | HCID 62412 | — |
| 반응물 | Propanenitrile, 2-amino- | HCID 411840 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | N-(1-cyanoethyl)-N'-(1,1-dimethylethyl)urea | HCID 21316847 | — |
반응 단계
To a stirring solution of 21.1 g (0.3 mole) 2-aminopropionitrile in 300 ml. dry tetrahydrofuran under a nitrogen atmosphere, there is added 30.7 g (0.3 mole) t-butyl isocyanate (97%). The resulting mixture is heated at reflux for five hours. At the end of this period, the tetrahydrofuran is removed at reduced pressure. The solid is recrystallized from methanol:water, 60:40, to give N-(1-cyanoethyl)-N'-(1,1-dimethylethyl)urea, m.p. 161°-3°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04156738 |
| 출처 데이터셋 | uspto-grants-1979_05 |
| ORD ID | ord-f6408094509d48d58ea659d4a8ff15bc |
| 출처 메모 | uspto-grants-1979_05 |