Ammonium Chloride → HCID 21322801, 화합물

HRID 26342노트

반응식

HRID 26342 반응식
[Cl-].[NH4+].[Cl:3][C:4]1[CH:16]=[C:15]([N+:17]([O-])=O)[CH:14]=[CH:13][C:5]=1[NH:6][CH2:7][CH:8]1[O:12][CH2:11][CH2:10][CH2:9]1>[Zn]>[ClH:3].[Cl:3][C:4]1[CH:16]=[C:15]([NH2:17])[CH:14]=[CH:13][C:5]=1[NH:6][CH2:7][CH:8]1[O:12][CH2:11][CH2:10][CH2:9]1

참가 물질

4

반응물 2

HCID 25517Ammonium ChlorideHCID 213228042-chloro-4-nitro-N-tetrahydrofurfurylaniline

생성물 1

HCID 21322801HCID 21322801, 화합물

시약·촉매·용매 1

HCID 23994Zinc촉매

실험 절차

3.0 g of ammonium chloride and 50 g of zinc powder are added to 150 ml of an aqueous-alcoholic solution (85% of alcohol and 15% of water). This mixture is heated to the reflux temperature, whilst stirring, and 0.1 mol (25.7 g) of 2-chloro-4-nitro-N-tetrahydrofurfurylaniline is then added gradually. When the addition has ended and the reaction mixture is decolorised, the latter is filtered and the filtrate is collected in 20 ml of ice-cooled hydrochloric acid. After cooling, the expected hydrochloride precipitates in the form of crystals. It is filtered off, washed with a small amount of ice-cooled absolute alcohol and dried in vacuo. It melts at about 170° C. with decomposition.

후처리

  1. temperatureThis mixture is heated to the reflux temperature
  2. additionWhen the addition
  3. filtrationthe latter is filtered
  4. customthe filtrate is collected in 20 ml of ice-
  5. temperaturecooled hydrochloric acid
  6. temperatureAfter cooling
  7. customthe expected hydrochloride precipitates in the form of crystals
  8. filtrationIt is filtered off
  9. washwashed with a small amount of ice-
  10. temperaturecooled absolute alcohol
  11. customdried in vacuo

출처 및 근거

ORD 기록
ord-7b37cd148ced4afebf90ae56e028634c
출처 데이터셋
uspto-grants-1979_04
특허 번호
US04149848

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