Dodecanoyl chloride → 4-(S)-Isopropyl-3-(1-oxododecyl)-2-oxazolidinone

HRID 263450

반응식

[CH:1]([C@H:4]1[CH2:8][O:7][C:6](=[O:9])[NH:5]1)([CH3:3])[CH3:2].[C:10](Cl)(=[O:22])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21]>>[CH:1]([C@H:4]1[CH2:8][O:7][C:6](=[O:9])[N:5]1[C:10](=[O:22])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])([CH3:3])[CH3:2]

참가 물질

반응물 2

HCID 8166Dodecanoyl chloride

HCID 7157133(4S)-4-(propan-2-yl)-1,3-oxazolidin-2-one

생성물 1

HCID 106865044-(S)-Isopropyl-3-(1-oxododecyl)-2-oxazolidinone수율 86.9%

실험 절차

Following the procedure described in Referential Example 3, but using 4-(S)-isopropyl-2-oxazolidinone (5.39 g) and dodecanoyl chloride (9.46 g), the desired compound (11.3 g) was obtained as a colorless oil.

출처 및 근거

ORD 기록: ord-9097b44110824cfa9e3abe25ac2ba08d
출처 데이터셋: uspto-grants-1997_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05643908

연결된 노트

불러오는 중…