(4S)-4-(propan-2-yl)-1,3-oxazolidin-2-one → 4-(S)-Isopropyl-3-(1-oxo-4-phenylbutyl)-2-oxazolidinone

HRID 263451노트

반응식

HRID 263451 반응식
[CH:1]([C@H:4]1[CH2:8][O:7][C:6](=[O:9])[NH:5]1)([CH3:3])[CH3:2].[C:10]1([CH2:16][CH2:17][CH2:18][C:19](Cl)=[O:20])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[CH:1]([C@H:4]1[CH2:8][O:7][C:6](=[O:9])[N:5]1[C:19](=[O:20])[CH2:18][CH2:17][CH2:16][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)([CH3:3])[CH3:2]

참가 물질

3

반응물 2

HCID 7157133(4S)-4-(propan-2-yl)-1,3-oxazolidin-2-oneHCID 117898654-Phenylbutanoyl Chloride

생성물 1

HCID 118079334-(S)-Isopropyl-3-(1-oxo-4-phenylbutyl)-2-oxazolidinone수율 98.6%

실험 절차

Following the procedure described in Referential Example 3, but using 4-(S)-isopropyl-2-oxazolidinone (6.88 g) and 4-phenylbutyryl chloride (6.88 g), the desired compound (10.23 g) was obtained as a colorless oil.

출처 및 근거

ORD 기록
ord-e0a655bfc9db4cc58c2a3876caa3aee4
출처 데이터셋
uspto-grants-1997_07
특허 번호
US05643908

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