Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Boc-Asp(O-cHex) Man(4-MBzl) → Asp(O-cHex) Man(4-MBzl)
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Boc-Asp(O-cHex) Man(4-MBzl) | HCID 131720065 | — |
| 용매 | Trifluoroacetic acid methylene chloride | HCID 21863450 | — |
| 생성물 | Asp(O-cHex) Man(4-MBzl) | HCID 131720066 | 107.8% |
반응 단계
Boc-Asp(O-cHex)-Man(4-MBzl) (52 g) was treated with 50% TFA/methylene chloride (400 mL) for 45 min at room temperature. The solvent was evaporated and chased several times with methylene chloride to eliminate traces of TFA. The product precipitated as its TFA salt upon addition of ether. The solid was collected and air dried to yield a white solid (46.7 g, 88%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05643872 |
| 출처 데이터셋 | uspto-grants-1997_07 |
| ORD ID | ord-ce3cf141d3b541f7b31680b4023b0da8 |
| 출처 메모 | uspto-grants-1997_07 |