Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,4-Bis[4-[(1-benzyloxyureido)methyl]phenoxy]butane → 1,4-Bis[4-[(1-hydroxyureido)methyl]phenoxy]butane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,4-Bis[4-[(1-benzyloxyureido)methyl]phenoxy]butane | HCID 54213011 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | HCID 178418390 | HCID 178418390 | — |
| 용매 | N,N-dimethylformamide ethanol | HCID 19794673 | — |
| 생성물 | 1,4-Bis[4-[(1-hydroxyureido)methyl]phenoxy]butane | HCID 54260419 | 62% |
반응 단계
1,4-Bis[4-[(1-benzyloxyureido)methyl]phenoxy]butane (1.94 g) was dissolved in 45 ml of dimethylformamide-ethanol (8:1), mixed with 0.29 g of 10% palladium carbon and then the mixture was stirred for 22 hours at room temperature in an atmosphere of hydrogen. The catalyst was removed by filtration using Celite, and the solvent was evaporated under a reduced pressure to obtain 0.84 g of 1,4-bis[4-[(1-hydroxyureido)methyl]phenoxy]butane.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05643931 |
| 출처 데이터셋 | uspto-grants-1997_07 |
| ORD ID | ord-0864f6c93e4148b1b8946b1cc0b66e5f |
| 출처 메모 | uspto-grants-1997_07 |