3,4-Diethoxybenzene-1-carbothioamide → HCID 18707257, 화합물

HRID 263607

반응식

HRID 263607 반응식
C([O:3][C:4]([C:6]1[CH:11]=[CH:10][N:9]=[C:8]([C:12](=O)[CH2:13]Br)[N:7]=1)=[O:5])C.[CH2:16]([O:18][C:19]1[CH:20]=[C:21]([CH:25]=[CH:26][C:27]=1[O:28][CH2:29][CH3:30])[C:22]([NH2:24])=[S:23])[CH3:17]>>[CH2:16]([O:18][C:19]1[CH:20]=[C:21]([C:22]2[S:23][CH:13]=[C:12]([C:8]3[N:7]=[C:6]([C:4]([OH:3])=[O:5])[CH:11]=[CH:10][N:9]=3)[N:24]=2)[CH:25]=[CH:26][C:27]=1[O:28][CH2:29][CH3:30])[CH3:17]

참가 물질

3

반응물 2

HCID 77452503,4-Diethoxybenzene-1-carbothioamideHCID 18707124HCID 18707124, 화합물

생성물 1

HCID 18707257HCID 18707257, 화합물

실험 절차

4-Ethoxycarbonyl-2-(α-bromoacetyl)pyrimidine and 3,4-diethoxythiobenzamide were subjected to the same reaction as in Example 1 and then to the same hydrolysis as in Example 147 to obtain 2-(3,4-diethoxyphenyl)-4-(4-carboxy-2-pyrimidyl)thiazole.

후처리

  1. customto the same hydrolysis as in Example 147

출처 및 근거

ORD 기록
ord-13ec25d149914186aa6cf4210e654d8f
출처 데이터셋
uspto-grants-1997_07
특허 번호
US05643932

연결된 노트

불러오는 중…