Acetic Acid → Methyl 3-hydroxy-2-methyl-5-nitro-3-indenylacetate

HRID 263619노트

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HRID 263619 반응식
[CH3:1][CH:2]1[CH2:10][C:9]2[C:4](=[CH:5][C:6]([N+:11]([O-:13])=[O:12])=[CH:7][CH:8]=2)[C:3]1=[O:14].[CH3:15][O:16][C:17]1[CH:25]=C2C(CC(C)C2=O)=CC=1.C([OH:30])C.C(O)(=O)C>O>[OH:14][C:3]1([CH2:25][C:17]([O:16][CH3:15])=[O:30])[C:4]2[C:9](=[CH:8][CH:7]=[C:6]([N+:11]([O-:13])=[O:12])[CH:5]=2)[CH:10]=[C:2]1[CH3:1]

참가 물질

6

반응물 4

HCID 176Acetic AcidHCID 702EthanolHCID 2311786-Methoxy-2-methyl-2,3-dihydro-1H-inden-1-oneHCID 21840586HCID 21840586, 화합물

생성물 1

HCID 53908697Methyl 3-hydroxy-2-methyl-5-nitro-3-indenylacetate

시약·촉매·용매 1

HCID 962Water용매

실험 절차

The procedure of Example 1C is followed using 2-methyl-6-nitro indanone in equivalent quantities in place of 6-methoxy-2-methyl-indanone used therein. After the mixture is condensed, 30 ml. of ethanol and 50 ml. of acetic acid are added. The mixture is then poured into 700 ml. of water. Extraction with ether gives methyl 3-hydroxy-2-methyl-5-nitro-3-indenylacetate.

후처리

  1. customcondensed, 30 ml
  2. additionThe mixture is then poured into 700 ml
  3. extractionExtraction with ether

출처 및 근거

ORD 기록
ord-492f7d423e534647afa22075b85263ca
출처 데이터셋
uspto-grants-1997_07
특허 번호
US05643959

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