Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phthalic Anhydride → 2-(8-Chloro-2-methylquinolin-5-yl)-1H-isoindole-1,3(2H)-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phthalic Anhydride | HCID 6811 | — |
| 반응물 | 1,2,3-Trichlorobenzene | HCID 6895 | — |
| 반응물 | 8-Chloro-2-methylquinolin-5-amine | HCID 21322927 | — |
| 생성물 | 2-(8-Chloro-2-methylquinolin-5-yl)-1H-isoindole-1,3(2H)-dione | HCID 21322916 | 83.3% |
반응 단계
95 g of trichlorobenzene was added to 23.3 g (0.12 mole) of 8-chloro-5-amino-quinaldine and 18.0 g (0.12 mole) of phthalic anhydride, and the mixture was reacted under reflux for 2 hours at the boiling point. After cooling, the precipitated crystals were separated by filtration, and dried to afford 32 g (0.10 mole) of 8-chloro-5-phthalimidoquinaldine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04150025 |
| 출처 데이터셋 | uspto-grants-1979_04 |
| ORD ID | ord-6b48f7d1232f46a9947bdd586f8143d2 |
| 출처 메모 | uspto-grants-1979_04 |