Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(Dimethylamino)butyric acid hydrochloride → 4-(Dimethylamino)butanoyl chloride hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(Dimethylamino)butyric acid hydrochloride | HCID 12691640 | — |
| 용매 | Thionyl Chloride | HCID 24386 | — |
| 생성물 | 4-(Dimethylamino)butanoyl chloride hydrochloride | HCID 19037478 | — |
반응 단계
10 g (60 mmol) of 4-dimethylaminobutyric acid hydrochloride (Janssen; Bruggen/Germany) are heated for approximately 3 h at 65° C. in 30 ml of SOCl2. SOCl2 is evaporated off and the residue is stirred to yield the title compound: TLC of a sample dissolved in methanol, Rf (U)=0.67; TLC of 4-dimethylaminobutyric acid hydrochloride, Rf (U)=0.50.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05643878 |
| 출처 데이터셋 | uspto-grants-1997_07 |
| ORD ID | ord-41aced89796c40338464e2b8252692e6 |
| 출처 메모 | uspto-grants-1997_07 |