Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosphorus pentachloride → Pyridine-3-sulfonyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosphorus pentachloride | HCID 24819 | — |
| 반응물 | 3-Pyridinesulfonic acid | HCID 69468 | — |
| 용매 | Benzene | HCID 241 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | Pyridine-3-sulfonyl chloride | HCID 3164136 | — |
반응 단계
3-pyridylsulfonic acid 5-5 (30 g, 0.188 mole) was added to PCl5 (46.8 g, 0.225 mole) suspended in 150 mL toluene and heated to reflux ovemight. The suspension was cooled and concentrated to yield a yellow oil, which was diluted with benzene, filtered through a pad of celite and concentrated to give 5-6 as a yellow oil that was used in the next step without purification. 1H NMR (300 MHz, CDCl3) a 9.27 (1H, s), 8.98 (1H, d, 8.35 (1H, d), 7.62 (1H, dd).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05646000 |
| 출처 데이터셋 | uspto-grants-1997_07 |
| ORD ID | ord-02b5186211584d53996df20fcf1dd224 |
| 출처 메모 | uspto-grants-1997_07 |