Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Cyanide → 4-amino-1-methylpiperidine-4-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Cyanide | HCID 8929 | — |
| 반응물 | N-Methyl-2-piperidone | HCID 13603 | — |
| 반응물 | Ammonium Hydroxide | HCID 14923 | — |
| 반응물 | Ammonium Chloride | HCID 25517 | — |
| 생성물 | 4-amino-1-methylpiperidine-4-carbonitrile | HCID 11434991 | — |
반응 단계
Using the procedure of Stage 1 of Example 1, 8 ml of ammonium hydroxide, 1.58 g of ammonium chloride and 1.23 g of sodium cyanide were reacted and 2.5 ml of 1-methylpiperidone were added. The mixture was stirred for 18 hours at ambient temperature, followed by extraction r3 times with chloroform. The organic phase was washed with salt water and dried to obtain 2.41 g of the expected product (orange-yellow syrup).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05646172 |
| 출처 데이터셋 | uspto-grants-1997_07 |
| ORD ID | ord-dc5971b1cb52476e8660ccef912bd5c0 |
| 출처 메모 | uspto-grants-1997_07 |