Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → ethyl (+/-)-5-decyl-alpha-phenyl-2H-tetrazole-2-acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Ethyl 2-(2-bromophenyl)acetate | HCID 2780092 | — |
| 반응물 | HCID 178442802 | HCID 178442802 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | ethyl (+/-)-5-decyl-alpha-phenyl-2H-tetrazole-2-acetate | HCID 19391039 | 34% |
반응 단계
The 5-decyl-1H-tetrazole, (4.0 g, 0.019 mol), triethylamine (2.9 mL, 0.021 mol) and ethyl 2-bromophenylacetate (5.09 g, 0.021 mol) were dissolved in 200 mL acetonitrile and heated to reflux for 2 hours. Cooled and concentrated in vacuo to give a yellow oil. Chromatography to separate the regioisomers gave ethyl (±)-5-decyl-α-phenyl-2H-tetrazole-2-acetate as a clear oil (2.40 g, 34%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05646170 |
| 출처 데이터셋 | uspto-grants-1997_07 |
| ORD ID | ord-2ea9bf9706214eb78de91b345ae6e45e |
| 출처 메모 | uspto-grants-1997_07 |