Tetradecanoic acid, 2-bromo-, ethyl ester → ethyl (+/-)-5-dodecyl-alpha-dodecyl-2H-tetrazole-2-acetate

HRID 264085

반응식

HRID 264085 반응식
[CH2:1]([C:13]1[NH:17][N:16]=[N:15][N:14]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].C(C1NN=NN=1)CCCCCCCCC.[CH2:33]([O:35][C:36](=[O:51])[CH:37](Br)[CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH3:49])[CH3:34].BrC1C=CC=CC=1CC(OCC)=O>>[CH2:1]([C:13]1[N:14]=[N:15][N:16]([CH:37]([CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH3:49])[C:36]([O:35][CH2:33][CH3:34])=[O:51])[N:17]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

참가 물질

5

반응물 4

HCID 85791Tetradecanoic acid, 2-bromo-, ethyl esterHCID 2780092Ethyl 2-(2-bromophenyl)acetateHCID 178442802HCID 178442802, 화합물HCID 178442834HCID 178442834, 화합물

생성물 1

HCID 53703025ethyl (+/-)-5-dodecyl-alpha-dodecyl-2H-tetrazole-2-acetate

실험 절차

When in the general procedure of Example 71 an appropriate amount of 5-dodecyl-1H-tetrazole was substituted for 5-decyl-1H-tetrazole and an appropriate amount of ethyl-2-bromomyristate was substituted for ethyl 2-bromophenylacetate, the title compound was obtained. 1H NMR (CDCl3): δ5.47-5.41 (m, 1H); 4.25-4.17 (q, 2H); 2.94-2.88 (t, 2H); 2.45-2.26 (m, 2H); 1.82-1.65 (m, 2H); 1.33-1.20 (m, 41H); and 0.90-0.85 (t, 6H) ppm.

출처 및 근거

ORD 기록
ord-9ab3c58b940544309debba30e344a990
출처 데이터셋
uspto-grants-1997_07
특허 번호
US05646170

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