Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Decyl chloroformate → N-[2-[4-(1-decanoxy-6-fluoro-1H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Decyl chloroformate | HCID 108727 | — |
| 반응물 | N-[2-[4-(6-fluoro1H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide | HCID 18467209 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | N-[2-[4-(1-decanoxy-6-fluoro-1H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide hydrochloride | HCID 18467279 | — |
반응 단계
A mixture of decanyl chloroformate (2.4 g, 11 mmol), and N-[2-[4-(6-fluoro-1H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide (3.9 g, 10 mmol) was warmed on the steam bath for 15 minutes. The reaction was allowed to cool to ambient temperature, and then ether was added to the residue. The resulting solid was filtered to afford N-[2-[4-(1-decanoxy-6-fluoro-1H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide hydrochloride.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05646161 |
| 출처 데이터셋 | uspto-grants-1997_07 |
| ORD ID | ord-7ace0fe5ba854382a5647425c2f04ab4 |
| 출처 메모 | uspto-grants-1997_07 |