2-Methoxyethylamine → HCID 54038932, 화합물
반응식
CO[C:3](=[O:18])[CH2:4][CH2:5][CH2:6][NH:7][C:8]([O:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[O:9].[CH3:19][O:20][CH2:21][CH2:22][NH2:23]>C(O)C>[CH3:19][O:20][CH2:21][CH2:22][NH:23][C:3](=[O:18])[CH2:4][CH2:5][CH2:6][NH:7][C:8]([O:10][CH2:11][C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)=[O:9]참가 물질
4
실험 절차
5.02 g of 4-benzyloxycarbonylaminobutyric acid methyl ester are stirred under reflux in 35 ml of ethanol with 15 ml of 2-methoxyethylamine for 5 days. The reaction mixture is concentrated by evaporation and the residue is purified by means of FC (240 g of silica gel, dichloromethane/methanol=95:5). The title compound is obtained: Rf (dichloromethane/methanol=95:5)=0.33.
후처리
- concentrationThe reaction mixture is concentrated by evaporation
- customthe residue is purified by means of FC (240 g of silica gel, dichloromethane/methanol=95:5)
출처 및 근거
- ORD 기록
- ord-7cce6d6c23a84d6bada430e2885e0194
- 출처 데이터셋
- uspto-grants-1997_07
- 특허 번호
- US05646143
반응 노트
불러오는 중…