Potassium Hydroxide → 2,11-dihydro-11-methyl-3H-s-triazolo[3,4-b][3]benzazepin-3-one

반응식

[CH3:1][CH:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[CH:6]=[CH:5][N:4]2[C:13](SC)=[N:14][N:15]=[C:3]12.[OH-:18].[K+]>>[CH3:1][CH:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[CH:6]=[CH:5][N:4]2[C:13](=[O:18])[NH:14][N:15]=[C:3]12

참가 물질

반응물 2

HCID 14797Potassium Hydroxide

HCID 2132353411-Methyl-3-methylthio-11H-s-triazolo[3,4-b][3]benzazepine

생성물 1

HCID 213233472,11-dihydro-11-methyl-3H-s-triazolo[3,4-b][3]benzazepin-3-one

실험 절차

11-Methyl-3-methylthio-11H-s-triazolo[3,4-b][3]benzazepine was treated with potassium hydroxide and the reaction mixture was treated as described. By this procedure was obtained 2,11-dihydro-11-methyl-3H-s-triazolo[3,4-b][3]benzazepin-3-one as crystals. Pale brown needles (as recrystallized from ethanol), m.p. 119°-120° C.

후처리

additionthe reaction mixture was treated

출처 및 근거

ORD 기록: ord-eaa933cba8a54ad894e6426fc27382a7
출처 데이터셋: uspto-grants-1979_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04150139

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