m-Chloroperbenzoic acid → 8-chloro-3-methylsulfinyl-11H-s-triazolo[3,4-b][3]benzazepine

반응식

[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[CH2:11][C:10]3=[N:12][N:13]=[C:14]([S:15][CH3:16])[N:9]3[CH:8]=[CH:7][C:6]=2[CH:17]=1.ClC1C=CC=C(C(OO)=[O:26])C=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[CH2:11][C:10]3=[N:12][N:13]=[C:14]([S:15]([CH3:16])=[O:26])[N:9]3[CH:8]=[CH:7][C:6]=2[CH:17]=1

참가 물질

반응물 2

HCID 70297m-Chloroperbenzoic acid

HCID 213235478-chloro-3-methylthio-11H-s-triazolo[3,4-b][3]benzazepine

생성물 1

HCID 213233338-chloro-3-methylsulfinyl-11H-s-triazolo[3,4-b][3]benzazepine

실험 절차

By a procedure similar to that described in Example 17, 8-chloro-3-methylthio-11H-s-triazolo[3,4-b][3]benzazepine was reacted with m-chloroperbenzoic acid to obtain 8-chloro-3-methylsulfinyl-11H-s-triazolo[3,4-b][3]benzazepine. Colorless needles (as recrystallized from methanol), m.p. 183°-185° C.

출처 및 근거

ORD 기록: ord-05ba0d03e464488d9512763ed6ecce82
출처 데이터셋: uspto-grants-1979_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04150139

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