Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-methylsulfonyl-11H-s-triazolo[3,4-b][3]benzazapine → 3-ethoxy-11H-s-triazolo[3,4-b][3]benzazepine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-methylsulfonyl-11H-s-triazolo[3,4-b][3]benzazapine | HCID 21323525 | — |
| 반응물 | 3-methylsulfinyl-11H-s-triazolo[3,4-b][3]benzazepine | HCID 21323529 | — |
| 반응물 | Ethanol sodium ethoxide | HCID 23706232 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-ethoxy-11H-s-triazolo[3,4-b][3]benzazepine | HCID 21323356 | — |
반응 단계
By a procedure similar to that described in Example 35, 0.245 g of 3-methylsulfinyl-11H-s-triazolo [3,4-b][3]benzazepine, in lieu of 3-methylsulfonyl-11H-s-triazolo[3,4-b][3]benzazepine, was reacted with 1.2 ml of 1 N-sodium ethoxide/ethanol in 2 ml of ethanol to obtain 3-ethoxy-11H-s-triazolo[3,4-b][3]benzazepine as crystals. Recrystallization from acetone yielded colorless needles, melting point 143°-144° C. The infrared absorption spectrum of this product was identical with that of the compound obtained in Example 35.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04150139 |
| 출처 데이터셋 | uspto-grants-1979_04 |
| ORD ID | ord-66aacf99ccc542b9aff3e8ef366f46b2 |
| 출처 메모 | uspto-grants-1979_04 |